Malither Injection contains:
Artemether …………………80mg
Arachis Oil BP …………...... Q.S.
Artemether is active against all Plasmodia including those which may be resistant to other antimalarials. Theschizonticidal activity of artemether is mainly due to destruction of the asexual Erythrocytic forms of P.falciparum and P.vivax. This is inhibition of protein synthesis during growth of trophozoites. There is no cross resistance with chloroquine. After intramuscular administration peak plasma concentrations are attained within about 6 hours.
Malither Injection is indicated in severe malaria including cerebral malaria and as a second line drug in chloroquine resistant malaria cases only.
Each pack of Malither Injection contain 6 x 1ml ampoules.
